This book provides a detailed account of the physico-chemical properties and biological functions of the outer membrane vesicles (OMVs) of different pathogenic and non-pathogenic Gram-negative bacteria. It also includes an authentic record of the first systematic study that discovered the mechanism of OMV formation by a pathogen, Vibrio cholerae, and proposed that the process represented a novel secretory activity of bacteria. Furthermore, the authors present clinical and laboratory data on the use of OMVs as immunogens, as effective and licensed vaccines against Neisseria...
This book provides a detailed account of the physico-chemical properties and biological functions of the outer membrane vesicles (OMVs) of differen...
Chronic arsenic exposure is a major environmental health concern currently affecting millions of people worldwide. Given the consequences of arsenic on human health, this study explores the effects of arsenic exposure in human population currently exposed to alarmingly high levels of arsenic. Genome-wide gene expression pattern analysis provides strong evidences for arsenic to be carcinogenic and to contribute to a well-defined spectrum of diseases. We also identify a potential bio-marker to arsenic induced carcinogenesis. This study thus provides critical insights into modus operandi of the...
Chronic arsenic exposure is a major environmental health concern currently affecting millions of people worldwide. Given the consequences of arsenic o...
To start with, we feel that we should explain why the book has been entitled Cholera Toxins. In fact, the enterotoxin secreted by Vibrio cholerae, which is p- marily responsible for causation of the disease, is conventionally known as or referred to as cholera toxin, or CT. By using the word "toxins" (in its plural form), we wanted to cover all of the different types of toxins--and not just CT--produced by V. cholerae. We could have used the title Toxins of Vibrio cholerae, but we believe that Cholera Toxins is simpler and equally as expressive. However, due to its relative importance, the...
To start with, we feel that we should explain why the book has been entitled Cholera Toxins. In fact, the enterotoxin secreted by Vibrio cholerae, whi...