This second review volume is a follow-up to the book “Engineering of Chemical Complexity” that appeared in 2013. Co-edited by the Nobel laureate Gerhard Ertl, this book provides a broad perspective over the current research aimed at understanding, the design and control of complex chemical systems of various origins, on the scales ranging from single molecules and nano-phenomena to macroscopic chemical reactors. Self-organization behavior and emergence of coherent collective dynamics in reaction-diffusion systems, in active soft matter and biochemical networks are discussed....