This book constitutes the refereed proceedings of the 22nd International Symposium on Algorithms and Computation, ISAAC 2011, held in Yokohama, Japan in December 2011. The 76 revised full papers presented together with two invited talks were carefully reviewed and selected from 187 submissions for inclusion in the book. This volume contains topics such as approximation algorithms; computational geometry; computational biology; computational complexity; data structures; distributed systems; graph algorithms; graph drawing and information visualization; optimization; online and streaming...

During recent years, major advances in surgical techniques, diagnostic methods, anesthesia and adjunctive treatment in the care of patients with subarachnoid hemorrhage have been achieved. Nevertheless, the overall outcome of patients with SAH cannot be regarded as satisfactory. The first part of the book concentrates on the pathogenetic mechanisms underlying vasospasm and edema, the principal causes of poor outcome. Recent progress in the field of membrane lipid metabolism has allowed the problem to be approached from an entirely new perspective. The possible participation of free radicals,...