In the Christian world of the fourth century, the family of St. Gregory of Nyssa was distinguished for its leadership in civic and religious affairs in the region of the Roman Empire known as Pontus. Cardinal Newman, in an essay on the trials of St. Basil, refers to the family circle which produced these two eminent Fathers as 'a sort of nursery of bishops and saints.' From St. Gregory's life of his sister, St. Macrina, a work included in this volume, we learn of the fortitude of the three preceding generations. On her death-bed, St. Macrina, recalling details of their family history, speaks...