This volume contains the proceedings of an NSF/Conference Board of the Mathematical Sciences (CBMS) regional conference on Hodge theory, complex geometry, and representation theory, held on June 18, 2012, at the Texas Christian University in Fort Worth, TX. Phillip Griffiths, of the Institute for Advanced Study, gave 10 lectures describing now-classical work concerning how the structure of Shimura varieties as quotients of Mumford-Tate domains by arithmetic groups had been used to understand the relationship between Galois representations and automorphic forms. He then discussed recent...