The fluoride ion (F) is the ionic form of the element fluorine, belonging to the halogen group of elements and one of the most abundant elements found in nature. Fluoride is a mineral that occurs naturally in many foods and water. Fluoride helps prevent tooth decay by making the tooth more resistant to acid attacks from plaque bacteria and sugars in the mouth. The fluoride has been widely used systematically and topically in the treatment of dental caries for its anti-cariogenic and antimicrobial properties. Systemic fluorides involve the process of ingestion, digestion, absorption and...