Antimicrobial resistance is a rising health risk of broad concern to countries and multiple sectors. It not only menaces the effective prevention and treatment of an ever-increasing range of infections but also results in reduced efficacy of antibacterial drugs. In intensively reared poultry, antibiotics are administered to whole flocks rather than individual animals. In addition to this, poultry farmers also use low doses of antibiotics as growth-promoting substances, which results in the high antibiotic selection pressure for resistance with a relatively high proportion of resistant...

Studies on the prevalence of the Extended Spectrum Beta Lactamase Enzyme Producing Enterobacteriaceae Group of Bacterial isolates from Bovine Milk were undertaken in the 100 samples, giving a prevalence rate of 14%. Three standard methods used were Combine disc diffusion test (CDDT), Double disc synergy test (DDST), and Enzyme MIC strip method. Among the three methods CDDT method showed maximum sensitivity, and the Ezy MIC strip method was found to be least sensitive. Multi-drug resistant profiles of ESBL-positive isolates were also observed against Amikacin, Cefuroxime, Cefixime, Ampicillin...

Antimicrobial resistance has become a burning issue in humans and animals. Extended-spectrum beta-lactamase is produced by certain bacteria which has the capacity to inhibit the effect of third-generation cephalosporins and beta-lactam antibiotics. E coli being an indicator organism if it produces extended-spectrum beta-lactamase enzyme in healthy broilers it could be very alarming. The present study was conducted on caecal samples collected from freshly slaughtered healthy broilers, characterized both phenotypically and genotypically. The beta lactamase enzyme obtained was studied for the...

The book deals with research on a pharmacokinetic study of Amikacin in goats. Multiple once daily dose intravenous and intramuscular administration of amikacin was done and concentration of the drug was estimated in plasma and urine at different time intervals. Kinetic parameters and dosage regimen of amikacin on first and last doses after multiple once-daily doses intravenous and intramuscular administration was also studied along with renal safety in goats.