Bowen's disease (BD) is a squamous cell carcinoma in situ whose association with human papilloma virus (HPV) infection has recently been demonstrated. In Tunisia, the association between MB and HPV infection has not been studied. The aim of our work was to study the epidemiological, anatomopathological and molecular features in extra-genital and genital MB. This was a retrospective descriptive study conducted between 2001-2020. Chromogenic in situ hybridization (CISH) analysis using HPV 6 /11, 16/18 and 31/33 probes was performed for all cases diagnosed with MB. Thirty-three skin biopsies...

Neoadjuvant treatment has shown its effectiveness in improving patient's outcome in locally advanced rectal carcinoma. Some patients show excellent response while others do not. We led a retrospective study with a rectal adenocarcinoma who had undergone initial MRI assessment and needed a neoadjuvant chemo-radiotherapy.The studied included 22 men and 8 women with a mean age of 57 years old. Eighteen patients had MRI after neoadjuvant treatment : tumoral response was considered subtle in 3 patients, almost complete in 3 patients and partial in 12 patients.Histological final assessment showed a...

Der Morbus Bowen (BD) ist ein Plattenepithelkarzinom in situ, dessen Assoziation mit einer Infektion mit dem humanen Papillomavirus (HPV) kürzlich nachgewiesen wurde. In Tunesien ist der Zusammenhang zwischen MB und HPV-Infektion nicht untersucht worden. Ziel unserer Arbeit war es, die epidemiologischen, anatomopathologischen und molekularen Merkmale bei extragenitalen und genitalen MB zu untersuchen. Dies war eine retrospektive, deskriptive Studie, die zwischen 2001 und 2020 durchgeführt wurde. Die chromogene In-situ-Hybridisierung (CISH) unter Verwendung von HPV 6 /11, 16/18 und 31/33...

The diagnosis as well as the management of fungal sinusitis is still very controversial. Several classifications have been proposed. The diagnosis is made on the basis of clinical, biological, radiological, mycological and pathological evidence. This book focuses on the main forms of fungal sinusitis and the different therapies proposed for these forms.

Nasosinus mucocelesNasosinus mucoceles are pseudocystic formations of the nasosinus cavities. The most frequent localizations are frontal and fronto-ethmoidal. Sphenoidal forms are more rare. The clinical manifestations are variable and depend essentially on the location of the mucocele and its extensions. Indeed, they have the particularity of having an expansive character responsible for the occurrence of complications. Their treatment is essentially surgical. This book focuses on the ethiopathogeny of these mucoceles and the modalities of their surgical treatment.