To date, chemotherapies in many post-clinical studies with natural compounds directed against colorectal cancerous cells are unfortunately very limited. Further research is warranted to identify the specificity and target ability, as well as precise molecular mechanisms of this natural biomolecule quercetin against colorectal cancer, while sparing non-cancerous/normal cells healthy. It is assumed that GA-loaded Chi nanoparticles will be broken down in the colonic fluid, and smaller cubic nanoparticles and other secondary carriers will form and transport the loaded gallic acid across the...
To date, chemotherapies in many post-clinical studies with natural compounds directed against colorectal cancerous cells are unfortunately very limite...
Despite a few reported clinical studies in CRC therapy, more extensive studies and investigations are necessary to prove an increased bioavailability via the encapsulation of gallic acid and quercetin into nanoformulation as compare to polyherbal extract. The complete mechanism as well as the interactions between these nanoformulation and cancer cells is still unknown. Future studies should focus on understanding the effects of polyherbal nanoformulation on colon and CRC cells through long term studies, as well as polyherbal nanoformulation interactions with both normal and cancer cells....
Despite a few reported clinical studies in CRC therapy, more extensive studies and investigations are necessary to prove an increased bioavailability ...
