Breast cancer is the second most common cancer among women worldwide. Hypoxia inducible factor- (HIF- ) is a heterodimer, which can acts as a key regulator to decrease the oxygen level in the cellular activity. Therefore, HIF- playing a vital role in the tumor progression. Here, we identified a novel peptide using insilco analysis. The present study was carried out of different peptides which were screened with insilco analysis. The identified peptide HIF9 binding to the p-aminosalicylic acid (PAS-B) domain and hinders the dimerization and transcription activity. Further, the quantification...
Breast cancer is the second most common cancer among women worldwide. Hypoxia inducible factor- (HIF- ) is a heterodimer, which can acts as a key reg...