Anthrone assay is a recent technique for polysaccharide estimation with several advantages like less interference. To employ this technique as routine quality control test in vaccine industry, validation of this method according to regulatory guidelines was necessary. In present study to validate this method and to generate reliable data, various experiments were designed for execution of different validation parameters.In the present work, the polysaccharide estimation using anthrone reagent has been found quite easier and reproducible. Range of linearity was observed to be 5-125 µg with...

Les produits à base de plantes, aujourd'hui, symbolisent la sécurité, contrairement aux produits synthétiques qui sont considérés comme dangereux pour l'homme et l'environnement. Cependant, les aveugles dépendants de la synthèse sont terminés et les gens retournent au naturel, avec l'espoir de sûreté et de sécurité. La phytothérapie est toujours le pilier d'environ 75 à 80% de la population mondiale, principalement dans les pays en développement, pour les soins de santé primaires, en raison d'une meilleure acceptabilité culturelle, d'une meilleure compatibilité avec le...

Supersaturable SMEDDS appeared to be an interesting approach to alleviate problems associated with oral delivery of Nebivolol. This can be achieved by using NEB-SMEDDS having the formula as Castor oil (30 %,v/v), Tween-80 (35 %,v/v), PEG-400 (35 %,v/v) and HPMC(5%)was successfully optimized to achieve higher release as well as bioavailability of NEB in F8 formulation of SMEDDS in comparison to plain drug suspension. Stability of the formulation was confirmed by thermodynamic stability study and long term stability study. The release and bioavailability from F8 SMEDDS was increased due to...

The present investigation involves formulation development and characterization pg matrix tablet for colon targeted delivery with a view to extended the drug release in colonic segment. The extended release matrix tablet were formulated by using the combination of release retardant polymer. The polymer used were hydroxypropylmethylcellulose, eudragit L-30.D55. tablet were prepared by wet granulation technique using water. The granules were subjected to pre-compression evaluation such as bulk density, tap density, compressibility index, hausners ratio, particle size distribution and loss on...

Die pflanzlichen Produkte symbolisieren heute Sicherheit, im Gegensatz zu den synthetischen, die für Mensch und Umwelt als unsicher gelten. Die auf Synthese angewiesenen Blinden sind jedoch vorbei und die Menschen kehren in der Hoffnung auf Sicherheit zu den Naturmenschen zurück. Die pflanzliche Medizin ist aufgrund der besseren kulturellen Akzeptanz, der besseren Verträglichkeit mit dem menschlichen Körper und der geringeren Nebenwirkungen in ihrer Studie immer noch die Hauptstütze von etwa 75-80% der Weltbevölkerung, hauptsächlich in den Entwicklungsländern, für die medizinische...