The world's most forward-looking CEOs recognize the real challenge facing business today: a fundamental shift in the nature of commerce. While sustainability programs, government action, and nonprofits are all parts of the solution, CEOs and other leaders must focus on social, environmental, and economic benefit--not only because it will make the world a better place, but because it will ensure lasting profitability and success in the business climate of tomorrow.

The Breakthrough Challenge is both an inspiring call-to-action and a guide for this transformation, based on the...