This book provides an in-depth examination of next-generation biomaterials that integrate dynamic responsiveness with regenerative medicine applications. The book highlights how 4D materials, capable of shape transformation in response to stimuli such as pH, temperature, light, or biochemical signals, are revolutionizing tissue engineering and therapeutic delivery. It explores shape-changing scaffolds designed to mimic native tissue environments, as well as advanced drug delivery platforms that enable controlled, targeted, and on-demand release of therapeutics. Multidisciplinary perspectives...