Diabetic neuropathy (DN) is a demonstrable disorder that occurs to peripheral and autonomic nervous systems. DN encompasses a wide heterogeneous group of clinical and subclinical syndromes. It is one of the major long term complication associated with diabetes that can cause considerable morbidity and mortality. The diagnosis of DN can vary significantly. Consequently millions of people with diabetes are affected with DN 50 to 75% of all ulceration and nontrauma amputations are a consequence of diabetic neuropathy, and cause more hospitalizations than all other diabetic complications....