The widespread applications of Platelet Rich Fibrin (PRF) solidify its place among autologous blood concentrate therapies as both a primary and supplementary medical tool. Earlier it was used as a scaffold matrix either alone or in combination with other biomaterials. Platelet Rich Fibrin (PRF) used alone or in combination with other biomaterials is safe and most successful. It is widely accepted minimally invasive procedure with very low risk and satisfactory results. Platelet Rich Fibrin (PRF) is effective due to gradual release of growth factors. It is an autologous preparation, it...