Nearly four decades after their discoveries, calponin and transgelin are now known as a family of actin-filament associated regulatory proteins with functions in regulating smooth muscle contractility and non-muscle cell motility. While calponin and transgelin were first found in smooth muscles, the past two decades have seen an increased interest in this family of proteins for functions in a broad range of non-muscle cells. This book concisely summarized what has been learned on the evolution, regulation and function of these actin cytoskeleton regulatory proteins and their isoforms. Through...