Clear aligner therapy (CAT) has become a widely accepted form of orthodontic treatment, and among the various factors that influence the effectiveness of clear aligners, the material used in their fabrication plays a crucial role. Advances in the chemistry of aligner materials have the potential to significantly transform the therapeutic applications of CAT. Without these advancements, the inherent biomechanical limitations of CAT could hinder its progress, causing clear aligners to underperform compared to traditional fixed orthodontic appliances. Clear aligners offer advantages over fixed...