Microorganisms play an unequivocal role in infecting root canal system. Endodontic infections occur and progress when the root canal system gets exposed to the oral environment by one reason or the other and simultaneously when there is fall in the body's immune response.Endodontic therapy's substantial purpose is to create a biologically appropriate environment within the root canal system that is conducive for the healing and maintenance of periradicular tissue health. Bacteria are one of the main factors causing disorders in the pulpal tissues, as they invade the endodontic space through...