Crossbred dairy cattle provide 27% of the total milk produced in the nation, which points out the importance of crossbreeding programme in India. Both male and female animal contributes equally to this condition but, male infertility is of major concern as a single bull is used to inseminate several thousands of cows. Further, in crossbred bulls, the incidence of poor semen quality and susceptibility of spermatozoa to cryodamages are very high. Recent evidence indicates that protein tyrosine phosphorylation (PTP) also occurs during cryopreservation and is associated with cryo-capacitation, a...