Infection control in a dental office is of utmost importance to ensure control of cross-contamination of life-threatening infections like Hepatitis, AIDS, and in current times of pandemic COVID-19. We need to ensure that the risk of transmissible infection to both the dentist, patients, and auxiliary staff should be minimized. As responsible clinicians our goals should be to reduce the number of pathogenic organism in the operatory. Office, Dentist, Patient, and Auxilary protocols should be strictly adhered to and followed during times of pandemic crisis.