Brain death is considered a major stress on the body that is associated with a massive inflammatory response or what is known as the "cytokine storm," which is characterized by the exaggerated release of pro-inflammatory cytokines. This heightened inflammatory response in brain dead organ donors leads to major disturbances in glucose homeostasis resulting in insulin resistance and systemic hyperglycemia. Acute hyperglycemia is intimately related to the inflammatory response and marks an increased risk of morbidity and mortality. Severe inflammation in brain dead donors can also lead to...
Brain death is considered a major stress on the body that is associated with a massive inflammatory response or what is known as the "cytokine storm,"...