Hepatic cirrhosis is the end stage of chronic liver disease, the majority of patients with cirrhosis die from life threatening complications. Recently, Mesenchymal stem cells show ability to differentiate into hepatocytes, stimulate the regeneration of endogenous parenchymal cells and enhance fibrous matrix degradation. Thus, this study aimed to evaluate the possible therapeutic effect of mesenchymal stem cells in thioacetamide (TAA) induced liver cirrhosis in rats. Animal model of liver cirrhosis was induced by intraperitoneal injection of thioacetamide.Ten albino rats weighting 100-120 g...
Hepatic cirrhosis is the end stage of chronic liver disease, the majority of patients with cirrhosis die from life threatening complications. Recently...