The ultimate goal of periodontal therapy is to regenerate the components of periodontium that was affected by periodontitis. The peptide P-15 is a synthetic clone of the 15-amino acid sequence of Type-I collagen, that plays an important role in the binding of cells, particularly fibroblasts and osteoblasts, and in the initiation of other cellular events like migration, proliferation, and differentiation that are necessary for periodontal regeneration. Based on this concept, the ABM/P-15 combination was developed. ABM/P-15 consists of an anorganic bovine-derived bone matrix (ABM) coated with a...

Today, with the high survival and success rates of implant therapy, the focus has shifted toward creating an esthetic restoration that is indistinguishable from natural teeth and is stable over time. Construction of an esthetically pleasing restoration involves not only harmonizing the size, shape, position, and colour of each prosthetic tooth with the adjacent teeth but also establishing peri-implant soft tissue compatibility with the surrounding gingiva and mucosa is also essential. This is particularly important in the anterior maxilla, also known as the "esthetic zone" of the oral...