Clarithromycin has a short half life 2.5-3.0 h, is used in the treatment of H. pylori infection in stomach, which is responsible for stomach cancer, peptic ulcer and duodenal ulcer. Clarithromycin is effective against H. pylori, when it has optimum concentration at the sit of action. Gastric residence time of the conventional clarithromycin dosage form is 0.5-2 h. This work contains an attempt to made floating alginate beads of clarithromycin by using the emulsion gelation method. The overall objective is that, once the drug-carrier material has been injected or otherwise implanted or taken...
Clarithromycin has a short half life 2.5-3.0 h, is used in the treatment of H. pylori infection in stomach, which is responsible for stomach cancer, p...