Liver is the main organ responsible for drug metabolism and appears to be sensitive target site for substances modulating biotransformation. Despite of tremendous advances in modern medicine, hepatic disease remains a worldwide health problem. The Indian subcontinent has a glorious tradition of usage of medicinal preparations from natural herbs. Leucas Cephalotes (Roth) Spreng (Family: Labiatae or Lamiaceae) rainy season weed, traditionally used in liver disorder according to ayurveda. However, the hepatoprotective potential of plant has never been reported. Owing to the lacunae of scientific...