The aim of this work was to study the different solid forms of Amantadine hydrochloride, possible co-crystals, produce new solid forms by using different selected solvents to produce new solid forms and diffraction quality crystals analyse the structure determine at where possible. By using different sophisticated equipment, methodology concluded that the new polymeric form such as SXD-Single Crystal X-ray Diffractions, PXRD- Powder X-ray Diffraction, DSC- Differential Scanning Calorimetry, STA-Simultaneous Thermal Analysis, TG-Thermo Gravimetric Analysis., VTPXRD-Variable Temperature Powder...

The present study enlightens to enhance the dissolution profile, absorption efficiency and bioavailability of water insoluble drugs like carvedilol. A novel "Powder Solution Technology" involves absorption and adsorption efficiency, which makes use of liquid medications admixed with suitable carriers and coating materials and formulated into a free flowing, dry looking, non adherent and compressible powder forms. Based upon a new mathematical model expression improved flow characteristics and hardness of the formulation has been achieved by changing the proportion of carrier and coating...