Mouse immune response to Plasmodium berghei infection: The pathogenesis of Plasmodium berghei in mice was investigated, varying inoculum parasite density and the type and time of chemotherapy. Parasitaemia, total and differential WBC counts were determined. Mice injected with 10^7 infected RBCs/ml died, while those injected with 10^5 and 10^3 infected RBCs/ml cleared the parasitaemia. Immunosuppression seemed to cause the observed inadequate and inappropriate immune response by 10^7 inoculum mice as high parasitaemia would enhance the parasite evasion mechanisms and host immunosuppression....