K.-E. Anderson, B. Bergdahl, G. Bodem, H.J. Dengler, S. Dutta, J.M. Foerster, K. Greeff, F. Grosse-Brockhoff, J. Kriegel
The pharmacokinetics of digitalis glycosides have been the subject of extensive re- view (IISALO, 1977; ARONSON, 1980; PERRIER et ai., 1977). Research on glycoside kinetics has progressed at a rapid pace, requiring continuing reevaluation of the state of our understanding of this problem. The present article focuses on the effect of disease states (renal, gastrointestinal, thyroid, and cardiac) on the absorption, distribution, and clearance of a number of digitalis glycosides. Evidence is critically reviewed, and interpreted with respect to possible clinical implications. A. Renal...
The pharmacokinetics of digitalis glycosides have been the subject of extensive re- view (IISALO, 1977; ARONSON, 1980; PERRIER et ai., 1977). Research...