This volume constitutes the proceedings of the Third Working Conference on Practice-Driven Research on Enterprise Transformation (PRET), held in Luxembourg, on September 6, 2010, as the industrial track of the 13th IEEE Conference on Commerce and Enterprise Computing (CEC 2011). The third edition of PRET marks a close collaboration between academia and practice. With the specific purpose of mutual learning and crossfertilization, top practitioners from industry were invited to submit case studies. To give them enough space for presentation, only four academic papers were accepted. These...