This book constitutes the thoroughly refereed post-conference proceedings of the First International Conference on Advances in New Technologies, Interactive Interfaces, and Communicability, held in Huerta Grande, Argentina, in October 2010. The 16 revised papers presented together with 3 keynote lectures were carefully reviewed and selected from numerous submissions. The topics addressed span the entire spectrum of design, e-commerce, e-learning, e-health, e-tourism, Web 2.0 and Web 3.0. and discuss the latest advances in the areas of accessibility, communicability, computer animation,...