Covering the developments in the field of purinergic and pyrimidinergic transmission, this work looks into the roles of those signaling systems in tissue function and pathophysiology and advances in developing potential new medications based on the modulation of P1 and P2 receptor signaling processes.
Covering the developments in the field of purinergic and pyrimidinergic transmission, this work looks into the roles of those signaling systems in tis...
Physiological, pharmacological and molecular biological data generated over the past three decades have demonstrated the existence of two major families of extracellular receptors, the P1, a family of four G-protein coupled receptors and the P2, a family of at least 12 receptors responsive to purine (ATP, ADP) and pyrimidine (UTP) nucleotides through which adenosine and ATP can function as extracellular messengers. The present two-part volume represents an integrated compendium of invited chapters by leading researchers in the area focusing on advances in the understanding of purinergic and...
Physiological, pharmacological and molecular biological data generated over the past three decades have demonstrated the existence of two major famili...