Aging induces a decrease in bone mass, and osteoporosis with its accompanying decrease in bone mass is widely recognized as a major public heath problem. Bone loss with increasing age may be due to decreased osteoblastic bone formation and increased osteoclastic bone resorption. Pharmacologic and nutritional factors may prevent bone loss with aging. Chemical compounds in food and plants, which regulate on bone metabolism, has been to be worthy of notice in the prevention of osteoporsis. Food chemical factors play a role in bone health and may be important in the prevention of bone loss with...

Signal transduction plays a pivotal role in cellular regulation. The second messenger is generated in cells once the first messenger binds to the receptors of plasma membranes. The second messenger, which was found firstly, is cyclic adenosine monophosphate. This book provides an examination of calcium signalling.

Carotenoids are natural pigments synthesized in plants, algae and photosynthetic bacteria by the polymerization of five-carbon isoprene units to provide a long and nearly symmetric conjugated chain of double bonds responsible for atypical chemical properties. Carotenoids can play an important role in the prevention and control of human health and disease conditions such as osteoporosis, cancer, cardiovascular problems, atherosclerosis, rheumatoid arthritis, muscular dystrophy, cataracts and certain neurological disorders. This book presents and discusses current research in the study of...

Regucalcin is a protein which is highly differentiated due to increased conservation of the regucalcin genes throughout evolution in vertebrates. Regucalcin plays a multifunctional role in cellular regulation, including an inhibitory role in protein kinases, protein phosphatases, NO synthase, nuclear DNA and RNA synthesis. Regucalcin suppresses an enhancement of cell proliferation and apoptotic cell death that are induced by various signalling factors. Regucalcin plays a pathophysiological role in many metabolic disorders in humans. This book introduces recent topics of regucalcin studies...

Zinc is one of the most abundant transition metals in the human body, and it has various benefits as an essential trace element in the regulation of the living body. This book introduces topics concerning the characteristics, uses and benefits of zinc. It helps us understand the various physiological-pathophysiological roles of zinc.

Carotenoids are natural pigments synthesized in plants, algae and photosynthetic bacteria by the polymerization of five-carbon isoprene units to provide a long and nearly symmetric conjugated chain of double bonds responsible for atypical chemical properties. Carotenoids can play an important role in the prevention and control of human health and disease conditions such as osteoporosis, cancer, cardiovascular problems, atherosclerosis, rheumatoid arthritis, muscular dystrophy, cataracts and certain neurological disorders. This book presents and discusses current research in the study of...