What are the different muscarinic acetylocholine receptor subtypes and how are they distributed in the airways and molecular signalling mechanisms? What is their function in inflammatory mechanisms and in neurogenic and non-neurogenic control of the airways? How is their gene expression regulated? The importance of muscarinic acetylocholine receptors for the pathophysiology and treatment of chronic inflammatory obstructive airways diseases calls for a comprehensive and integrated overview of knowledge to address such questions, to discuss the role of these receptor subtypes in diseases such...