In the year 2085, mankind has finally colonized the moon. The ISO ONE penal colony has become the off-world home to 300 of the earth's most vicious murderers, rapists and felons. Inside ISO ONE, something has gone terribly wrong. An incident of unspeakable savagery leads to the mysterious, completely inexplicable disappearance of every living being inside the colony. Three prison guards are sent to investigate the mystery of ISO ONE. There, they will confront a force so alien, so completely evil, they will learn that hell is not beneath us. It is 240,000 miles above.

By 2018, America has been ravaged by terrorism and biological warfare. One particular bio-weapon, dubbed the ""Wrath of God,"" has virtually destroyed the nation- inflicting its victims with wildly varying symptoms and creating horrifying genetic mutations. Those who survive the plague fight for life day to day, struggling to maintain a semblance of society. Rebecca Artemis has been infected by ""the Wrath"" in an astonishingly macabre way. Like a vampire, she feeds upon blood to maintain her own deteriorating blood cells. Consumed by guilt over the atrocities she commits, she feverishly...