Mutts centers on the day-to-day adventures of two companion animals: a dog named Earl and a cat named Mooch. Earl and Mooch interact with each other, their human guardians and a large cast of neighborhood animals.

Mutts explores the special bond between animals and their guardians, and the endearing friendship of Earl, the dog, and Mooch, the cat. It strikes a delicate balance between joy, fun and responsible social commentary. Mutts has been recognized for its distinctive style, heartwarming humor and compassionate advocacy for animal issues.