The spatio-temporal dynamics of the cell, in other words the cell movements and deformations, were for a long time assimilated to random fluctuations. However a minute observation revealed the existence of recurring patterns of deformations for rounded cell types. The aim of this study is to investigate the spatio-temporal dynamics of another phenotypically different and important cell, the fibroblast. This investigation is based on image analysis and the development of specific strategies to track down the spatio-temporal cell signature. Interpretation of the results is performed by mean of...