Certain drugs having poor solubility, degradation in the alkaline pH, absorbed from the proximal part of Gastrointestinal Tract and causes irritation in the stomach. Due to this reason, drug should not achieve 100% bioavailability. To overcome these, Gastroretentive drug delivery system is a promising approach for achieving prolonged and predictable drug delivery profile. Floating drug delivery is an attempt which has been made to retained the drug in the stomach as a way of increasing retention time. Such type of novel drug delivery reduces the dosing frequency which is patient compliant and...

The Cefetamet Pivoxil Hydrochloride is a highly Bitter Drug which is available as Tablet formulation in the Indian market. A successful approach is made to develop the Dispersible Tablet and Dry Syrup formulation in which the Bitter taste of Cefetamet Pivoxil Hydrochloride is masked. The Dispersible Tablet and Dry Syrup are useful for the Geriatric and Pediatric who are unable to take the dose in Tablet formulation. The Taste masked Cefetamet Pivoxil Hydrochloride Tablet and Dry syrup is not available in the National market. The process developed is such that the formulation can be...