In summary, a series of diversely functionalized 40 imidazopyrazoles and bridgehead imidazopyrazoles have been synthesized via versatile straightforward synthetic routes. Our work is introduced in four parts. Part I includes synthesies of imidazopyrazole thione and its neculophilic substitution. Part II is about addition, condensation reactions and formation of hydrazienyl derivatives. Part III is about chalcone formation and its cyclization. Part IV is about assessment of anti-diabetic activity of newely synthesised. All compounds were characterized by IR, 1 HNMR, 13CNMR, and mass spectra as...