Antiphospholipid syndrome is a disorder of the immune system that is characterized by excessive clotting of blood and adverse pregnancy outcome that negatively affect women's quality of life. patient with antiphospholipid syndrome exposed in their life to social burden, psychological suffering, fear of the unknown, many types of threats, many hospitalization stressors they exposed to it during their hospital stay, and unsettled quality of life from all aspects; physical, social, psychological, and economic aspects.