Future epidemics are inevitable, and it takes months and even years to collect fully annotated data. The sheer magnitude of data required for machine learning algorithms, spanning both shallow and deep structures, raises a fundamental question: how big data is big enough to effectively tackle future epidemics? In this context, active learning, often referred to as human or expert-in-the-loop learning, becomes imperative, enabling machines to commence learning from day one with minimal labeled data. In unsupervised learning, the focus shifts toward constructing advanced machine learning...