Gonorrhoea is an ancient disease mentioned in the third book of Moses in the Bible, also in the 18th dynasty of Luxor in Egypt. Gonorrhoea is the second prevalent sexually transmitted disease . WHO considered gonorrhoea as a major health problem, Center of Disease Control and prevention (CDC) mentioned gonorrhoea as a Super Pug , since gonorrhoea has remarkable ability to cause repeated infection in the same host and has extraordinary ability to develop resistance to all clinically used antibiotics. However, Cephalosporins especially 3rd generation Ceftriaxone is still considered the first...