Langerhans' cells are dendritic cells that have a somewhat irregular shape. They are cells of myeloid origin that are known to be involved in immune responses. They are insinuated between keratinocytes but are not joined to them by cell junctions.Langerhans' cells are abundant in the epidermis, containing large granules called Birbeck granules. They are normally present in lymph nodes, and can be found in other organs in the condition Histiocytosis.

Vascular anomalies are broadly categorized into two groups: tumors and malformations. They are large and complex group of lesions and extremely different as evidenced by medical literature. A thorough medical history and physical examination is necessary for accurate diagnosis of vascular lesions. There are several different vascular tumors, but infantile hemangiomas are the most common. Others tumors that will be discussed include tuft angiomas, pyogenic granulomas, angiosarcomas, and kaposiform hemangioendotheliomas. Management of vascular tumors depends on their medical history, diagnosis,...