Most frequent Round Cell Tumors are Non-Hodgkins Lymphoma, Neuroblastoma, Ewing/PNET and Rhabdomyosarcoma. Neuroblastoma, Retinoblastoma, Wilms Tumor, Hepatoblastoma show presentation in early childhood while Rhabdomyosarcoma is seen throughout childhood. The majority of round cells tumors have male predominance. Identification and accurate diagnosis of a tumor is an art and necessiates complete knowledge of cellular, biochemical , molecular events and pathogenesis of the tumor. Round cell tumors are characterised by round and relatively undifferentiated cell. Differential diagnosis of round...