Traumatic brain injury (TBI) is a disorder that destructs brain functions and results in severe cognitive and emotional disturbances. It is a common reason for mortality and morbidity of human beings globally. Recent researches indicated that the transplanted mesenchymal stem cells (MSCs) can migrate and accommodate into the injured brain sites to contribute in the healing of the damaged brain tissue. The underlying mechanisms behind the action of MSCs are the anti- apoptotic and anti-inflammatory properties of these cells beside their ability to release neurotrophic and angiogenic factors....