CHAPTER I: INTRODUCTION: Incidence of R-plasmids and their transmissibility in bacteria which harbor the genes for multi Drug resistance and heavy metal tolerance among bacterial population. CHAPTER II: REVIEW OF LITERATURE: Indicators of Microbial water quality, Development of indicators, Development of indicators, Key fecal indicator micro-organisms, Microbiological and Physiochemical Aspects of water quality, Antibiotic resistance among thermo tolerant bacterial indicators, Heavy metal tolerance among thermotolerant bacterial indicators, Plasmid mediated resistance in antibiotics and metal...