Accumulated evidence has demonstrated that both oxidative stress and abnormal cytokine production, especially tumor necrosis factor- (TNF), IL-1beta, IL-6 play important etiological roles in the pathogenesis of hepatotoxicity. Aqueous extraction of Tagetes patula linn that have both antioxidant and anti-inflammation properties, represent promising therapeutic interventions for hepatotoxicity. Animals were randomly assigned into five groups, containing six animals in each group. Group I- Control.; Group II - Ethanol (0.5ml/100g) p.o for 28 consecutive days; Group III- Silymarin 100mg/kg +...
Accumulated evidence has demonstrated that both oxidative stress and abnormal cytokine production, especially tumor necrosis factor- (TNF), IL-1beta,...
