Microorganisms play a significant role in the development and progression of pulp and periapical diseases. The primary objective of endodontic therapy is to eradicate root canal infection and create an environment in which any residual microorganisms cannot survive. This can be achieved by employing a combination of aseptic treatment techniques, chemomechanical preparation of the root canal, antimicrobial irrigating solutions and intracanal medicaments. Intracanal medicaments would include any agent with intended pharmacological action introduced in the root canal. While irrigating solutions...