An immature tooth with early irreversible pulp involvement presents with thin divergent or parallel dentinal walls. This situation creates clinical challenges in disinfection, and as a result, affects the long-term outcome of the treatment. Traditionally, calcium hydroxide has been used as the intra-canal medicament in apexification procedures. However, because of its high pH it will cause necrosis of tissues that can potentially differentiate into new pulp. Revascularization of a pulp-like tissue for dentine deposition will allow further development of the root and dentinal structure with a...