The present study was done to evaluate the pharmacokinetic parameters of ciprofloxacin following single dose of oral and i.v route of administration and estimating the residual level and withdrawal period. The safety evaluation on liver and kidney following multiple doses of ciprofloxacin orally in dual purpose chicken was done. The study was conducted in thirty day old Indian Rock-3 birds (n=210), a dual purpose chicken strain of White Plymouth Rock developed by Veterinary College, Bengaluru. Liquid Chromatography-tandem Mass Spectrometry, which provides superior specificity and sensitivity...

The study was taken up to evaluate the pharmacological and toxicological property of Phaseolus lunatus (P. lunatus) plant. Phytochemical analysis revealed the presence of carbohydrates, proteins, saponins, alkaloids, flavonoids and phenolic compounds. The study was conducted to evaluate the in vivo anti-inflammatory property of the plant extract using carrageenan induced paw oedema and the extract at the doses of 400 and 600 mg/kg is having significant anti-inflammatory activity. In vivo analgesic activity was conducted by using acetic acid induced writhings as peripheral pain model and the...

Drug repurposing and repositioning is a process of identifying new therapeutic use (s) for the available and existing older drugs. Therapeutically, this has become a popular and effective strategy in recent years, in discovering or developing drug molecules with new pharmacological action and therapeutic indications. The drug repurposing strategy is efficient, economical and less time consuming and is thought to be an effective alternative approach to traditional drug discovery process. With the discovery of novel biological targets, the drug repositioning would maximize the success rate of...