The main objective of this study is to formulate and evaluate of Bioadhesive pulsatile drug delivery system of an antilipidemic drug. In order to achieve a improved therapeutic efficacy. The present research works describe the combination of Bio adhesive pulsatile principle are very suitable for site and time specific. Gastroretentive drug delivery is an approach to prolong gastric residence time, thereby targeting site specific drug release in the upper gastrointestinal tract (GIT) for local or systemic effects. Several gastro retentive drug delivery approaches being designed and developed...

Recently fast dissolving tablet attracted a great deal of attractions. The fast dissolving tablet is useful for geriatric patients are suffering from tremors and dysphasia, Pediatric patients who are unable to swallow, travelling patients suffering from motion sickness and diarrohea and mentally challenged patients, bedridden patients.The fast dissolving tablet used for improving bioavailability of poorly soluble drug due to absorption of drug into oral cavity and also due to pregastic absorption of dispersed drugs into saliva.

Self-micro emulsifying mouth dissolving film is a new dosage form, an integration of self-micro emulsifying drug delivery system in a fast mouth dissolving film. Self micro emulsifying drug delivery system(SMEDDS) is an isotropic mixture of oil, surfactant, and co-surfactant. Upon mild agitation followed by dilution in an aqueous medium (gastrointestinal fluids), this system can form fine oil-in-water (o/w) microemulsion. Due to their small droplet size, they can provide a large surface area of absorption and improve the oral bioavailability of drugs more than any other drug delivery system....

Der selbstmikroemulgierende mundauflösende Film ist eine neue Darreichungsform, eine Integration des selbstmikroemulgierenden Wirkstoffabgabesystems in einen sich schnell auflösenden Film. Das selbstmikroemulgierende Arzneimittelabgabesystem (SMEDDS) ist eine isotrope Mischung aus Öl, Tensid und Co-Tensid. Durch leichtes Rühren und anschließende Verdünnung in einem wässrigen Medium (Magen-Darm-Flüssigkeit) kann dieses System eine feine Öl-in-Wasser-Mikroemulsion (O/W) bilden. Aufgrund ihrer geringen Tröpfchengröße bieten sie eine große Absorptionsoberfläche und verbessern die...

Le film auto-micro-émulsifiant à dissolution buccale est une nouvelle forme de dosage, une intégration du système d'administration de médicaments auto-micro-émulsifiants dans un film à dissolution buccale rapide. Le système d'administration de médicaments auto-micro-émulsifiants (SMEDDS) est un mélange isotrope d'huile, de tensioactif et de co-tensioactif. Après une légère agitation suivie d'une dilution dans un milieu aqueux (fluides gastro-intestinaux), ce système peut former une fine microémulsion huile-dans-eau (H/E). En raison de la petite taille de leurs gouttelettes,...